Abstract Background The tumour stroma -or tumour microenvironment- is an important constituent of solid cancers and it is thought to be one of the main obstacles to quantitative translation of drug activity between the preclinical and clinical phases of drug development.The tumour-stroma relationship has been described as being both pro- and antitu
Category: Ankle; Ankle Arthritis Introduction/Purpose: Osseointegration is an important determinant of clinical success following the insertion of a orthopaedic implants.The success of osseointegration is an important predictor of the long-term clinical success of many implants, especially total joint arthroplasties.Total ankle arthroplasty (TAA) i
The safe and efficient function of critical national infrastructure (CNI) relies on the accurate demand forecast.Cyber-physical system-based demand forecasting systems (CDFS), typically found in CNI (such as energy, water, and transport), are highly vulnerable to being compromised under false data injection attacks (FDIAs).The problem is that the m
In macroeconomics, an emerging discussion of alternative monetary systems addresses the dimensions of systemic risk in advanced financial systems.Monetary regime changes with the aim ORG BLACK SOY BEANS of achieving a more sustainable financial system have already been discussed in several European parliaments and were the subject of a referendum i